Putting this in perspective, eating a portion of grapefruit would have a similar effect on the aforementioned liver enzymes. So neutralizing P450 enzymes should be viewed as a minor side effect of cannabidiol. However, if you are taking pharmaceutical drugs and wish to take CBD, you should discuss any potential complications regarding reduced P450 enzyme activity with your doctor and/or pharmacist.
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Overall, your skin experiences plenty of stress and damage throughout the day. It’s just natural. It’s the organ that’s keeping your body all together and protects you from free radicals in the air of your environment. Opting for a CBD lotion, even on your best days, gives your skin an extra boost. It can reinvigorate skin that’s dull and dry, and it can be especially useful after a day in the sun or a long trip. 
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